A Simple Technique to Improve Microcrystals Using Gel Exclusion of Nucleation Inducing Elements
A technique is described for generating large well diffracting crystals from conditions that yield microcrystals.Crystallization using this vegas golden knights background technique is both rapid (crystals appear in <1 h) and robust (48 out of 48 co-crystallized with a fragment library, compared with 26 out of 48 using conventional hanging drop)